Restricted active site docking by enzyme-bound substrate enforces the ordered cleavage of prothrombin by prothrombinase.

Hacisalihoglu A, Panizzi P, Bock PE, Camire RM, Krishnaswamy S
J Biol Chem. 2007 282 (45): 32974-82

PMID: 17848548 · PMCID: PMC2292459 · DOI:10.1074/jbc.M706529200

MeSH Terms (6)

Binding Sites Factor Xa Mutation Prothrombin Substrate Specificity Thromboplastin

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