Structural basis of enantioselective inhibition of cyclooxygenase-1 by S-alpha-substituted indomethacin ethanolamides.

Harman CA, Turman MV, Kozak KR, Marnett LJ, Smith WL, Garavito RM
J Biol Chem. 2007 282 (38): 28096-105

PMID: 17656360 · DOI:10.1074/jbc.M701335200

MeSH Terms (15)

Amides Animals Binding Sites Crystallography, X-Ray Cyclooxygenase 1 Dose-Response Relationship, Drug Indomethacin Kinetics Models, Chemical Models, Molecular Molecular Conformation Mutagenesis Protein Binding Sheep Stereoisomerism

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