A critical role of non-active site residues on cyclooxygenase helices 5 and 6 in the control of prostaglandin stereochemistry at carbon 15.

Valmsen K, Boeglin WE, Järving R, Järving I, Varvas K, Brash AR, Samel N
J Biol Chem. 2007 282 (38): 28157-63

PMID: 17652088 · DOI:10.1074/jbc.M704950200

MeSH Terms (15)

Amino Acid Sequence Animals Anthozoa Binding Sites Carbon Cell Line Insecta Kinetics Models, Chemical Molecular Sequence Data Mutagenesis, Site-Directed Prostaglandin-Endoperoxide Synthases Prostaglandins Protein Isoforms Stereoisomerism

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