Regulator of G Signaling 16 is a marker for the distinct endoplasmic reticulum stress state associated with aggregated mutant alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin deficiency.

Hidvegi T, Mirnics K, Hale P, Ewing M, Beckett C, Perlmutter DH
J Biol Chem. 2007 282 (38): 27769-80

PMID: 17635928 · DOI:10.1074/jbc.M704330200

MeSH Terms (15)

alpha 1-Antitrypsin Animals Endoplasmic Reticulum HeLa Cells Hepatocytes Humans Liver Mice Mice, Transgenic Models, Biological Mutation Protein Conformation Protein Denaturation RGS Proteins Signal Transduction

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