A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase.

Chui CK, Brumme ZL, Brumme CJ, Yip B, Phillips EJ, Montaner JS, Harrigan PR
Clin Infect Dis. 2007 44 (11): 1503-8

PMID: 17479950 · DOI:10.1086/517499

MeSH Terms (19)

Adult Alleles Anti-HIV Agents Antiretroviral Therapy, Highly Active Contraindications Dideoxynucleosides Drug Hypersensitivity Female Genetic Testing Genotype HIV Reverse Transcriptase HLA-B Antigens Humans Male Mutation Prevalence Reverse Transcriptase Inhibitors Sensitivity and Specificity Sequence Analysis, RNA

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