Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.

Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP
J Biol Chem. 2007 282 (27): 19831-43

PMID: 17468100 · DOI:10.1074/jbc.M702290200

MeSH Terms (11)

8-Hydroxy-2'-Deoxyguanosine Amino Acid Substitution Archaeal Proteins Crystallography, X-Ray Deoxyguanosine DNA, Archaeal DNA Polymerase beta Hydrogen Bonding Mutation, Missense Protein Structure, Tertiary Sulfolobus solfataricus

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