Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib.

Blobaum AL, Marnett LJ
J Biol Chem. 2007 282 (22): 16379-90

PMID: 17434872 · DOI:10.1074/jbc.M609883200

MeSH Terms (17)

Amino Acid Substitution Animals Cyclooxygenase 1 Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Diclofenac Humans Kinetics Male Membrane Proteins Mice Models, Molecular Mutation, Missense Protein Binding Protein Structure, Tertiary Sheep Time Factors

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