A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier.

Moran JL, Qiu H, Turbe-Doan A, Yun Y, Boeglin WE, Brash AR, Beier DR
J Invest Dermatol. 2007 127 (8): 1893-7

PMID: 17429434 · DOI:10.1038/sj.jid.5700825

MeSH Terms (8)

Animals Arachidonate 12-Lipoxygenase Codon, Nonsense Epidermis Genotype Ichthyosiform Erythroderma, Congenital Mice Permeability

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