Inhibitory control in children with frontal infarcts related to sickle cell disease.

Christ SE, Moinuddin A, McKinstry RC, DeBaun M, White DA
Child Neuropsychol. 2007 13 (2): 132-41

PMID: 17364570 · DOI:10.1080/09297040500346563

Evidence from past studies indicates that children with traumatic brain injury experience difficulties with inhibitory control. Less is known about inhibitory control in children with frontal brain injury related to cerebral infarction. We compared the inhibitory performance of children with frontal infarcts related to sickle cell disease with that of a control group of children with sickle cell disease but no history of cerebral infarction. On a stimulus-response reversal task, children with frontal infarcts made significantly more accuracy errors in the inhibitory condition than controls. Findings from this study and from previous research suggest that impairments in inhibitory control are common following frontal injury in a range of pediatric populations.

MeSH Terms (18)

Adolescent Anemia, Sickle Cell Attention Cerebral Infarction Child Female Frontal Lobe Genotype Hemoglobin, Sickle Humans Inhibition (Psychology) Male Neuropsychological Tests Orientation Pattern Recognition, Visual Psychomotor Performance Reaction Time Reversal Learning

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