A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

Rivera N, Everett-Grueter CA, Edgerton DS, Rodewald T, Neal DW, Nishimura E, Larsen MO, Jacobsen LO, Kristensen K, Brand CL, Cherrington AD
J Pharmacol Exp Ther. 2007 321 (2): 743-52

PMID: 17308040 · DOI:10.1124/jpet.106.115717

MeSH Terms (13)

Aniline Compounds Animals beta-Alanine C-Peptide Dogs Dose-Response Relationship, Drug Female Gluconeogenesis Glucose Glycogenolysis Liver Male Receptors, Glucagon

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