Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence.

Cho YJ, Kozekov ID, Harris TM, Rizzo CJ, Stone MP
Biochemistry. 2007 46 (10): 2608-21

PMID: 17305317 · PMCID: PMC2581467 · DOI:10.1021/bi061381h

MeSH Terms (10)

Base Sequence CpG Islands Cross-Linking Reagents Deoxyguanosine DNA Hydrogen Bonding Molecular Conformation Nucleic Acid Conformation Protons Torsion Abnormality

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