PAR1, but not PAR4, activates human platelets through a Gi/o/phosphoinositide-3 kinase signaling axis.

Voss B, McLaughlin JN, Holinstat M, Zent R, Hamm HE
Mol Pharmacol. 2007 71 (5): 1399-406

PMID: 17303701 · PMCID: PMC2846178 · DOI:10.1124/mol.106.033365

MeSH Terms (12)

Blood Coagulation Blood Platelets Calcium Enzyme Activation GTP-Binding Protein alpha Subunits, Gi-Go Humans Phosphatidylinositol 3-Kinases Platelet Activation Platelet Glycoprotein GPIIb-IIIa Complex Receptor, PAR-1 Receptors, Thrombin Signal Transduction

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