Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.

Indra AK, Castaneda E, Antal MC, Jiang M, Messaddeq N, Meng X, Loehr CV, Gariglio P, Kato S, Wahli W, Desvergne B, Metzger D, Chambon P
J Invest Dermatol. 2007 127 (5): 1250-60

PMID: 17301838 · DOI:10.1038/sj.jid.5700672

MeSH Terms (15)

9,10-Dimethyl-1,2-benzanthracene Animals Carcinogens Cell Transformation, Neoplastic Epidermis Gene Expression Regulation, Neoplastic Keratinocytes Mice Mice, Transgenic Nevus, Pigmented Papilloma PPAR gamma Retinoid X Receptor alpha Skin Neoplasms Tetradecanoylphorbol Acetate

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