Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

Bailey DG, Dresser GK, Leake BF, Kim RB
Clin Pharmacol Ther. 2007 81 (4): 495-502

PMID: 17301733 · DOI:10.1038/sj.clpt.6100104

MeSH Terms (20)

Adult Anticoagulants Beverages Citrus paradisi Cross-Over Studies Data Interpretation, Statistical Double-Blind Method Drug Interactions Female Flavanones Furocoumarins HeLa Cells Hesperidin Histamine H1 Antagonists Humans Male Middle Aged Organic Anion Transporters Reproducibility of Results Terfenadine

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