Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.

Reese M, Sánchez-Pedregal VM, Kubicek K, Meiler J, Blommers MJ, Griesinger C, Carlomagno T
Angew Chem Int Ed Engl. 2007 46 (11): 1864-8

PMID: 17274084 · DOI:10.1002/anie.200604505

MeSH Terms (9)

Antineoplastic Agents Epothilones Magnesium Magnetic Resonance Spectroscopy Microtubules Models, Molecular Solutions Structure-Activity Relationship Tubulin

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