Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells.

Sarthy AV, Morgan-Lappe SE, Zakula D, Vernetti L, Schurdak M, Packer JC, Anderson MG, Shirasawa S, Sasazuki T, Fesik SW
Mol Cancer Ther. 2007 6 (1): 269-76

PMID: 17237286 · DOI:10.1158/1535-7163.MCT-06-0560

MeSH Terms (18)

Alleles Apoptosis Cell Death Cell Survival Cell Transformation, Neoplastic Clone Cells G2 Phase Genes, Neoplasm Genes, ras Humans Inhibitor of Apoptosis Proteins Microtubule-Associated Proteins Mitosis Mutant Proteins Neoplasm Proteins Polyploidy RNA, Small Interfering Survivin

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