Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane.

Liu L, Watanabe K, Fang Q, Williams KM, Guengerich FP, Pegg AE
Chem Res Toxicol. 2007 20 (1): 155-63

PMID: 17226938 · DOI:10.1021/tx600257g

MeSH Terms (10)

Binding Sites Chromatography, High Pressure Liquid Electrophoresis, Polyacrylamide Gel Escherichia coli Ethylene Dibromide Half-Life Mutagens O(6)-Methylguanine-DNA Methyltransferase Point Mutation Spectrometry, Mass, Electrospray Ionization

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