K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells.

Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS
Blood. 2007 109 (9): 3945-52

PMID: 17192389 · PMCID: PMC1874575 · DOI:10.1182/blood-2006-09-047530

MeSH Terms (14)

Animals Cell Proliferation Extracellular Signal-Regulated MAP Kinases Granulocyte-Macrophage Colony-Stimulating Factor Hematopoietic Stem Cells Mice Mice, Transgenic Myeloproliferative Disorders Neoplastic Stem Cells Point Mutation Proto-Oncogene Proteins p21(ras) Ribosomal Protein S6 Kinases Signal Transduction STAT5 Transcription Factor

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