A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.

Tchekneva EE, Rinchik EM, Polosukhina D, Davis LS, Kadkina V, Mohamed Y, Dunn SR, Sharma K, Qi Z, Fogo AB, Breyer MD
J Am Soc Nephrol. 2007 18 (1): 103-12

PMID: 17151334 · DOI:10.1681/ASN.2006020164

MeSH Terms (20)

Albuminuria Animals Diabetic Nephropathies Disease Models, Animal Ethylnitrosourea Female Genes, Dominant Genetic Predisposition to Disease Genetic Testing Humans Insulin Kidney Male Mice Mice, Inbred C57BL Mice, Mutant Strains Mutagens Mutation Phenotype Sensitivity and Specificity

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