Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM
Cancer Res. 2006 66 (20): 9837-44

PMID: 17047044 · DOI:10.1158/0008-5472.CAN-06-0890

MeSH Terms (18)

Animals Cell Growth Processes Cell Transformation, Neoplastic Colonic Neoplasms Disease Progression Female Gene Expression Regulation, Neoplastic Genes, APC Gene Silencing Intestinal Mucosa Male Mice Mice, Transgenic Mutation Neoplasm Invasiveness Protein-Serine-Threonine Kinases Receptor, Transforming Growth Factor-beta Type II Receptors, Transforming Growth Factor beta

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