Human immunodeficiency virus type 1 resistance to the small molecule maturation inhibitor 3-O-(3',3'-dimethylsuccinyl)-betulinic acid is conferred by a variety of single amino acid substitutions at the CA-SP1 cleavage site in Gag.

Zhou J, Chen CH, Aiken C
J Virol. 2006 80 (24): 12095-101

PMID: 17035324 · PMCID: PMC1676313 · DOI:10.1128/JVI.01626-06

MeSH Terms (12)

Amino Acid Substitution Anti-HIV Agents Cell Line, Tumor Drug Resistance, Viral Gene Products, gag HIV-1 Humans Mutagenesis Succinates Triterpenes Virus Assembly Virus Replication

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