The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells.

Sai J, Walker G, Wikswo J, Richmond A
J Biol Chem. 2006 281 (47): 35931-41

PMID: 16990258 · PMCID: PMC2950015 · DOI:10.1074/jbc.M605883200

MeSH Terms (15)

Amino Acid Motifs Cell Movement Cell Separation Chemokines Chemotaxis Enzyme Activation GTP Phosphohydrolases HL-60 Cells Humans Interleukin-8 Ligands Mutation Protein Structure, Tertiary Receptors, Interleukin-8B Signal Transduction

Connections (4)

This publication is referenced by other Labnodes entities: