HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis.

Zuo Y, Matsusaka T, Zhong J, Ma J, Ma LJ, Hanna Z, Jolicoeur P, Fogo AB, Ichikawa I
J Am Soc Nephrol. 2006 17 (10): 2832-43

PMID: 16988066 · DOI:10.1681/ASN.2005080878

MeSH Terms (12)

AIDS-Associated Nephropathy Animals Female Gene Products, nef Genes, vpr Glomerulosclerosis, Focal Segmental Male Mice Mice, Inbred C57BL Mice, Transgenic nef Gene Products, Human Immunodeficiency Virus Podocytes

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