Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.

Fujimoto Y, Torres TP, Donahue EP, Shiota M
Diabetes. 2006 55 (9): 2479-90

PMID: 16936196 · DOI:10.2337/db05-1511

MeSH Terms (22)

Animals Blood Glucose Carbonates Carrier Proteins Diabetes Mellitus, Type 2 Fatty Acids, Nonesterified Glucagon Glucokinase Glucose Glucose-6-Phosphatase Glucosides Glycogen Glycogen Synthase Hyperglycemia Insulin Liver Liver Glycogen Male Muscle, Skeletal Phosphorylases Rats Rats, Zucker

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