Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity.

Ritchie MD, Haas DW, Motsinger AA, Donahue JP, Erdem H, Raffanti S, Rebeiro P, George AL, Kim RB, Haines JL, Sterling TR
Clin Infect Dis. 2006 43 (6): 779-82

PMID: 16912956 · DOI:10.1086/507101

MeSH Terms (25)

Adult Alkynes Anti-HIV Agents Aryl Hydrocarbon Hydroxylases Benzoxazines Case-Control Studies Chemical and Drug Induced Liver Injury Cyclopropanes Cytochrome P-450 CYP2B6 Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Female Genes, MDR Genetic Variation Genotype HIV-1 HIV Infections Humans Liver Liver Diseases Male Nevirapine Oxazines Oxidoreductases, N-Demethylating Reverse Transcriptase Inhibitors

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