The clot thickens.

Fogo AB
Kidney Int. 2006 70 (4): 620-1

PMID: 16900220 · DOI:10.1038/sj.ki.5001721

Vascular sclerosis has been linked to many risk factors, including smoking, family history, low birth weight, and hypertension. In interesting studies, Goforth et al. show an increased rate of mutations in thrombophilic molecules in patients with vascular sclerosis in renal biopsies, suggesting yet another mechanism.

MeSH Terms (15)

Biopsy Diabetes Mellitus Factor V Humans Hypertension Kidney Methylenetetrahydrofolate Reductase (NADPH2) Mutation Nephrosclerosis Plasminogen Activator Inhibitor 1 Prothrombin Renal Artery Risk Factors Sclerosis Smoking

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