Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors.

Yang S, Qu S, Perez-Tores M, Sawai A, Rosen N, Solit DB, Arteaga CL
Cancer Res. 2006 66 (14): 6990-7

PMID: 16849543 · DOI:10.1158/0008-5472.CAN-06-1042

MeSH Terms (17)

Animals Cell Survival Down-Regulation ErbB Receptors Female Gene Expression Regulation, Neoplastic HSP90 Heat-Shock Proteins Humans Ligands Lung Neoplasms Mice Mice, Inbred BALB C Mutation Oncogene Protein v-cbl Transfection Transplantation, Heterologous Ubiquitin

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