Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.

Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB
J Am Soc Nephrol. 2006 17 (7): 1962-9

PMID: 16769745 · DOI:10.1681/ASN.2006020165

MeSH Terms (11)

Animals Collagen Type IV Disease Models, Animal Glomerular Basement Membrane Kidney Glomerulus Mice Mice, Transgenic Nephritis, Hereditary Protein Isoforms Survival X Chromosome

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