Sex differences in cerebral laterality of language and visuospatial processing.

Clements AM, Rimrodt SL, Abel JR, Blankner JG, Mostofsky SH, Pekar JJ, Denckla MB, Cutting LE
Brain Lang. 2006 98 (2): 150-8

PMID: 16716389 · DOI:10.1016/j.bandl.2006.04.007

Sex differences on language and visuospatial tasks are of great interest, with differences in hemispheric laterality hypothesized to exist between males and females. Some functional imaging studies examining sex differences have shown that males are more left lateralized on language tasks and females are more right lateralized on visuospatial tasks; however, findings are inconsistent. Here we used functional magnetic resonance imaging to study thirty participants, matched on task performance, during phonological and visuospatial tasks. For each task, region-of-interest analyses were used to test differences in cerebral laterality. Results indicate that lateralization differences exist, with males more left lateralized during the phonological task and showing greater bilateral activity during the visuospatial task, whereas females showed greater bilateral activity during the phonological task and were more right lateralized during the visuospatial task. Our data provide clear evidence for differences in laterality between males and females when processing language versus visuospatial information.

MeSH Terms (13)

Adult Brain Mapping Case-Control Studies Dominance, Cerebral Female Humans Image Processing, Computer-Assisted Language Magnetic Resonance Imaging Male Photic Stimulation Sex Characteristics Task Performance and Analysis

Connections (2)

This publication is referenced by other Labnodes entities:

Links