Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors.

Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE
Genes Dev. 2006 20 (11): 1496-510

PMID: 16705038 · PMCID: PMC1475762 · DOI:10.1101/gad.1417406

MeSH Terms (12)

Adenocarcinoma Animals Base Sequence DNA Primers Down-Regulation ErbB Receptors Humans Lung Neoplasms Magnetic Resonance Imaging Mice Phosphorylation Protein-Tyrosine Kinases

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