Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4.

Irimia A, Zang H, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M
Biochemistry. 2006 45 (19): 5949-56

PMID: 16681366 · DOI:10.1021/bi052511+

MeSH Terms (9)

Base Sequence Biopolymers Calcium Cations, Divalent Diphosphates DNA-Directed DNA Polymerase DNA Primers Models, Molecular Sulfolobus solfataricus

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