Interleukin-4 induces 15-lipoxygenase-1 expression in human orbital fibroblasts from patients with Graves disease. Evidence for anatomic site-selective actions of Th2 cytokines.

Chen B, Tsui S, Boeglin WE, Douglas RS, Brash AR, Smith TJ
J Biol Chem. 2006 281 (27): 18296-306

PMID: 16675443 · DOI:10.1074/jbc.M603484200

MeSH Terms (14)

Arachidonate 15-Lipoxygenase Autoimmunity Dexamethasone Enzyme Induction Fibroblasts Gene Expression Regulation, Enzymologic Graves Disease Humans Interferon-gamma Interleukin-4 Interleukin-13 Orbit Organ Specificity Th2 Cells

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