Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.

Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC, de Paulis T, Conn PJ
J Pharmacol Exp Ther. 2006 318 (1): 173-85

PMID: 16608916 · DOI:10.1124/jpet.106.102046

MeSH Terms (17)

Allosteric Regulation Animals Anti-Anxiety Agents Antipsychotic Agents Biphenyl Compounds CHO Cells Cricetinae Dose-Response Relationship, Drug Excitatory Postsynaptic Potentials Indans Male Mice Mice, Inbred C57BL Motor Activity Rats Rats, Sprague-Dawley Receptors, Metabotropic Glutamate

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