Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides.

Duca M, Guianvarc'h D, Oussedik K, Halby L, Garbesi A, Dauzonne D, Monneret C, Osheroff N, Giovannangeli C, Arimondo PB
Nucleic Acids Res. 2006 34 (6): 1900-11

PMID: 16598074 · PMCID: PMC1447649 · DOI:10.1093/nar/gkl126

MeSH Terms (11)

Antineoplastic Agents, Phytogenic DNA DNA Damage DNA Footprinting DNA Topoisomerases, Type II Drug Delivery Systems Enzyme Inhibitors Etoposide Humans Oligodeoxyribonucleotides Topoisomerase II Inhibitors

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