Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.

Paulsson JF, Andersson A, Westermark P, Westermark GT
Diabetologia. 2006 49 (6): 1237-46

PMID: 16570161 · DOI:10.1007/s00125-006-0206-7

MeSH Terms (17)

Amyloid Amyloidosis Animals Apoptosis Guinea Pigs Humans Insulin-Secreting Cells Islet Amyloid Polypeptide Islets of Langerhans Transplantation Mice Mice, Nude Mice, Transgenic Microscopy, Immunoelectron Protein Precursors Protein Processing, Post-Translational Rabbits Transplantation, Heterologous

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