2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.

Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M
Biochemistry. 2006 45 (13): 4141-52

PMID: 16566588 · PMCID: PMC2553321 · DOI:10.1021/bi052322r

MeSH Terms (4)

Arabinonucleotides Nucleic Acid Conformation Nucleic Acid Heteroduplexes Ribonuclease H

Connections (1)

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