Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis.

Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T
J Exp Med. 2006 203 (3): 513-8

PMID: 16533887 · PMCID: PMC2118228 · DOI:10.1084/jem.20052458

MeSH Terms (14)

Animals Blood Coagulation Factor Inhibitors Blood Vessels Brain Ischemia Factor XI Deficiency Factor XII Factor XII Deficiency Female Fibrin Hemostasis Male Mice Mice, Knockout Thrombosis

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