Influence of site of expression on the fetal gamma delta T-cell receptor repertoire.

Kyes S, Pao W, Hayday A
Proc Natl Acad Sci U S A. 1991 88 (17): 7830-3

PMID: 1652766 · PMCID: PMC52397 · DOI:10.1073/pnas.88.17.7830

The sequences of productive T-cell gamma/delta receptor transcripts were compared in different murine fetal tissues. Differences from tissue to tissue suggest that the sequence repertoires are at least in part the products of selection, presumably through interaction of T cells bearing the gamma delta receptor with fetal self-ligands.

MeSH Terms (18)

Animals Base Sequence Fetus Gene Expression Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor Gene Rearrangement, T-Lymphocyte Intestines Liver Macromolecular Substances Mice Mice, Inbred BALB C Mice, Inbred C57BL Molecular Sequence Data Multigene Family Oligonucleotide Probes Receptors, Antigen, T-Cell Skin Thymus Gland

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