Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.

Katz DA, Carr R, Grimm DR, Xiong H, Holley-Shanks R, Mueller T, Leake B, Wang Q, Han L, Wang PG, Edeki T, Sahelijo L, Doan T, Allen A, Spear BB, Kim RB
Clin Pharmacol Ther. 2006 79 (3): 186-96

PMID: 16513443 · DOI:10.1016/j.clpt.2005.11.003

MeSH Terms (15)

Adult Alleles Atrasentan Carrier Proteins Female Genotype HeLa Cells Humans Liver-Specific Organic Anion Transporter 1 Male Middle Aged Organic Anion Transporters Phenotype Pyrrolidines Transfection

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