Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage.

Robinson MJ, Martin BA, Gootz TD, McGuirk PR, Moynihan M, Sutcliffe JA, Osheroff N
J Biol Chem. 1991 266 (22): 14585-92

PMID: 1650363

MeSH Terms (16)

Animals Anti-Infective Agents Catalysis Cell Line Cell Survival Cricetinae Cricetulus DNA DNA Topoisomerases, Type II Drosophila melanogaster Electrophoresis, Agar Gel Etoposide Fluoroquinolones Hydrolysis Molecular Structure Quinolones

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