Adult mice lacking the p53/p63 target gene Perp are not predisposed to spontaneous tumorigenesis but display features of ectodermal dysplasia syndromes.

Ihrie RA, Bronson RT, Attardi LD
Cell Death Differ. 2006 13 (9): 1614-8

PMID: 16485031 · DOI:10.1038/sj.cdd.4401871

MeSH Terms (15)

Aging Animals Disease Susceptibility Ectodermal Dysplasia Epithelium Hair Heterozygote Membrane Proteins Mice Mice, Knockout Neoplasms Phosphoproteins Skin Trans-Activators Tumor Suppressor Protein p53

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