BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.

Yang J, Amiri KI, Burke JR, Schmid JA, Richmond A
Clin Cancer Res. 2006 12 (3 Pt 1): 950-60

PMID: 16467110 · PMCID: PMC2668250 · DOI:10.1158/1078-0432.CCR-05-1220

MeSH Terms (19)

Animals Apoptosis Cell Line, Tumor Cell Proliferation Dose-Response Relationship, Drug Drug Evaluation, Preclinical Humans I-kappa B Kinase Imidazoles In Vitro Techniques Melanoma Mice Mitochondria NF-kappa B Quinoxalines Signal Transduction Structure-Activity Relationship Time Factors Tumor Cells, Cultured

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