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Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.

Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV
Genes Dev. 2006 20 (2): 253-66

PMID: 16418487 · PMCID: PMC1356115 · DOI:10.1101/gad.1360106

MeSH Terms (18)

Animals Cell Differentiation Conserved Sequence Diabetes Mellitus, Type 2 Enteroendocrine Cells Female Gene Expression Regulation, Developmental Homeodomain Proteins Intestinal Mucosa Male Mice Mice, Inbred C57BL Mice, Transgenic Mutation Organogenesis Pancreas Regulatory Sequences, Nucleic Acid Trans-Activators

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