The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases.

Vander Kooi CW, Ohi MD, Rosenberg JA, Oldham ML, Newcomer ME, Gould KL, Chazin WJ
Biochemistry. 2006 45 (1): 121-30

PMID: 16388587 · PMCID: PMC2570371 · DOI:10.1021/bi051787e

MeSH Terms (17)

Amino Acid Sequence Binding Sites Carrier Proteins Crystallography, X-Ray Dimerization DNA Repair Enzymes Humans Models, Chemical Molecular Sequence Data Nuclear Proteins Polyubiquitin Protein Structure, Tertiary RNA, Small Nuclear RNA Splicing Factors Substrate Specificity Ubiquitin-Conjugating Enzymes Ubiquitin-Protein Ligases

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