Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.

Cho YJ, Kim HY, Huang H, Slutsky A, Minko IG, Wang H, Nechev LV, Kozekov ID, Kozekova A, Tamura P, Jacob J, Voehler M, Harris TM, Lloyd RS, Rizzo CJ, Stone MP
J Am Chem Soc. 2005 127 (50): 17686-96

PMID: 16351098 · PMCID: PMC2631571 · DOI:10.1021/ja053897e

MeSH Terms (16)

Acrolein Carbon Isotopes CpG Islands Cross-Linking Reagents Deoxyguanosine DNA DNA Adducts Hydrogen Bonding Isotope Labeling Models, Molecular Nitrogen Isotopes Nuclear Magnetic Resonance, Biomolecular Oligonucleotides Oligopeptides Stereoisomerism Substrate Specificity

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