Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.

Goodenough AK, Kozekov ID, Zang H, Choi JY, Guengerich FP, Harris TM, Rizzo CJ
Chem Res Toxicol. 2005 18 (11): 1701-14

PMID: 16300379 · PMCID: PMC3135970 · DOI:10.1021/tx050141k

MeSH Terms (5)

Chromatography, High Pressure Liquid Deoxyguanosine Drug Stability Oligonucleotides Temperature

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