Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.

Gajewski TF, Sosman J, Gerson SL, Liu L, Dolan E, Lin S, Vokes EE
Clin Cancer Res. 2005 11 (21): 7861-5

PMID: 16278409 · DOI:10.1158/1078-0432.CCR-05-0060

MeSH Terms (21)

Adult Aged Aged, 80 and over Antineoplastic Agents Antineoplastic Agents, Alkylating Antineoplastic Combined Chemotherapy Protocols Carbon Monoxide Carmustine Cohort Studies Disease Progression Female Guanine Humans Leukocytes, Mononuclear Male Melanoma Middle Aged Neoplasm Metastasis O(6)-Methylguanine-DNA Methyltransferase Time Factors Treatment Outcome

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