The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia.

Moreno-Miralles I, Pan L, Keates-Baleeiro J, Durst-Goodwin K, Yang C, Kim HG, Thompson MA, Klug CA, Cleveland JL, Hiebert SW
J Biol Chem. 2005 280 (48): 40097-103

PMID: 16199529 · DOI:10.1074/jbc.M506855200

MeSH Terms (26)

Alleles Animals Bone Marrow Cells Bone Marrow Transplantation Cyclin-Dependent Kinase Inhibitor p16 DNA Flow Cytometry Genes, Reporter Green Fluorescent Proteins Humans Leukemia, Myeloid, Acute Liver Mice Mice, Transgenic Mutagenesis NIH 3T3 Cells Oncogene Proteins, Fusion Plasmids Promoter Regions, Genetic Protein Binding Recombinant Fusion Proteins Spleen Time Factors Transfection Translocation, Genetic Tumor Suppressor Protein p14ARF

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