Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks.

McClendon AK, Rodriguez AC, Osheroff N
J Biol Chem. 2005 280 (47): 39337-45

PMID: 16188892 · DOI:10.1074/jbc.M503320200

MeSH Terms (12)

Antigens, Neoplasm DNA, Superhelical DNA-Binding Proteins DNA Replication DNA Topoisomerases, Type II Humans In Vitro Techniques Kinetics Models, Biological Plasmids Recombinant Proteins Substrate Specificity

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