A biosynthetic pathway generating 12-hydroxy-5,8,14-eicosatrienoic acid from arachidonic acid is active in mouse skin microsomes.

Du L, Yermalitsky V, Hachey DL, Jagadeesh SG, Falck JR, Keeney DS
J Pharmacol Exp Ther. 2006 316 (1): 371-9

PMID: 16169934 · DOI:10.1124/jpet.105.093922

MeSH Terms (15)

8,11,14-Eicosatrienoic Acid Animals Animals, Newborn Arachidonic Acid Aryl Hydrocarbon Hydroxylases Chromatography, Liquid Cytochrome P450 Family 2 Lipoxygenase Mass Spectrometry Mice Microsomes Mixed Function Oxygenases NADP Skin Stereoisomerism

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